The Center is supported by the CDC and sponsored by the American Association of Neuropathologists.

Contact & Mailing

Mailing Instructions:

General Instructions

All specimens should be shipped using Federal Express.  Specimens should be shipped Monday through Thursday to avoid Saturday and holiday delivery.  For tracking purposes, a copy of the Federal Express Airbill should be faxed (216-368-2546 or 216-368-4090) to the NPDPSC on the day of shipment

All shipments should be addressed to:

National Prion Disease Pathology Surveillance Center
Institute of Pathology
Case Western Reserve University
2085 Adelbert Road, Room 418
Cleveland, Ohio 44106-4907
Tel: 216-368-0587
Email: cjdsurv@case.edu

Please send a completed Test Request Form with all samples. The NPDPSC requires any available clinical information when sending tissue and/or blood to assist us in making the most accurate diagnosis possible. The NPDPSC is CLIA certified and fully compliant with HIPAA regulations.


Instructions by Type of Sample

Blocks/slides:
Slides should be placed in plastic slide holders and mailed in a bubble wrap envelope.  Blocks should be mailed in a bubble wrap envelope.
Blood: Ship at room temperature in protective bubble wrap or Styrofoam on the day that the blood is collected. The NPDPSC processes blood samples for special cases only, and all blood samples must be accompanied by a signed Testing and Reporting Policies Form as well as clinical and/or family history. Please contact the Center Manager at 216-368-0819 for more information if needed.
CSF: Ship using a Styrofoam container with sufficient dry ice (5lbs/24hrs). The NPDPSC requests a urine sample for research purposes with all CSF samples if available.
Urine: Ship double boxed using a Styrofoam container with sufficient dry ice (5lbs/24 hrs).
Fixed tissue: Ship double boxed without dry ice.
Frozen tissue: Ship double-boxed using a Styrofoam container with sufficient dry ice (5lbs/24hrs). Please include a signed Testing and Reporting Policies Form with frozen tissue samples. The NPDPSC sequences the prion protein gene for all positive cases. Please contact the Center Manager at 216-368-0819 for more information if needed.

Note: Frozen and fixed tissue should be shipped using a UN class 6.2 approved container. Please, send fixed and frozen tissue samples in separate containers to avoid freezing of the fixed tissue which results in artifacts.
For More Information

General and shipping questions can be directed to the NPDPSC
at 216-368-0587 or by email cjdsurv@case.edu.

Specific questions related to completing the Federal Express Airbill should be directed to Federal Express
at 1-800-463-3339 or http://www.fedex.com.

Specific questions related to shipping infectious material should be directed to World Health Organization (WHO) at http://www.who.int/emc/pdfs/emc97_3.pdf.  (Note: You must have Adobe Acrobat Reader to view this file.)  Examples for filling out the Dangerous Goods Declarations without dry ice can be found on page 17 and for Dangerous Goods Declarations with dry ice on page 18.

If you need the Adobe Acrobat Reader, you may download the reader for free by clicking on the icon to the right.